Propargyl p-toluenesulfonate

CAS NO.：6165-76-0
Empirical Formula: C10H10O3S
Molecular Weight: 210.25
MDL number: MFCD01462194
SAFETY DATA SHEET (SDS)
Update Date: 2023-07-04 17:14:15

What is Propargyl p-toluenesulfonate?

Chemical properties

Clear colorless to brown liquid

The Uses of Propargyl p-toluenesulfonate

Propargyl p-toluenesulfonate is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

The Uses of Propargyl p-toluenesulfonate

Protected Propargyl. A possible genotoxic compound that can affect the bacterial and mammalian cell systems.

The Uses of Propargyl p-toluenesulfonate

Propargyl p-toluenesulfonate can be used as an initiator in the synthesis of linear and cyclic poly(2-isopropyl-2-oxazoline)s by cationic ring-opening polymerization of 2-isopropyl-2-oxazoline.
It can also be used as a reagent to synthesize:

2-hydroxy-4-pentynoic acid by an alkylation reaction with diethyl 2-acetamidomalonate followed by subsequent hydrolysis, decarboxylation, diazotization, and hydroxylation reactions.
Furan derivatives by Pd-catalyzed reaction with acylchromates.

Properties of Propargyl p-toluenesulfonate

Boiling point:	117-121°C 0,3mm
Density	1.215 g/mL at 20 °C (lit.)
refractive index	n20/D 1.530
Flash point:	117-121°C/0.3mm
storage temp.	2-8°C
solubility	soluble in Chloroform, Dichloromethane, DMSO, Ethyl Acetate
form	Liquid
color	Clear colorless to brown
Water Solubility	Soluble in Chloroform, Dichloromethane, DMSO, Ethyl Acetate. Not miscible in water.
BRN	1212957

Safety information for Propargyl p-toluenesulfonate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.