PROCATEROL HYDROCHLORIDE
- CAS NO.：62929-91-3
- Empirical Formula: C16H23ClN2O3
- Molecular Weight: 326.82
- MDL number: MFCD04221378
- EINECS: 263-763-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is PROCATEROL HYDROCHLORIDE?
Description
Procaterol is an agonist of β2-adrenergic receptors (β2-ARs). It binds to (Kd = 46 pM), and is selective for, β2-ARs over β1-ARs (Kd = 4,000 pM). Procaterol binds more potently to β2-ARs in isolated guinea pig lung than to β1-ARs in isolated guinea pig cardiac ventricle in the presence (IC50s = 175 and 1,660 nM, respectively) and absence of GTP (; IC50s = 55.1 and 1,660 nM, respectively). It inhibits contractions induced by acetylcholine in isolated guinea pig trachea (EC50 = 10.5 nM). In vivo, procaterol inhibits histamine-induced airflow obstruction in a guinea pig model of ovalbumin-sensitized asthma when administered via inhalation at a dose of 10 μg/ml.
The Uses of PROCATEROL HYDROCHLORIDE
Procaterol Hydrochloride is a short-acting pulmonary β2-agonist for asthma treatment.
The Uses of PROCATEROL HYDROCHLORIDE
adrenergic agonists
What are the applications of Application
Procaterol hydrochloride is a very potent and specific β2 agonist
General Description
Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.
Biological Activity
Specific and very potent β 2 agonist.
Biochem/physiol Actions
β2-adrenoceptor agonist; bronchodilator.
storage
Store at RT
Properties of PROCATEROL HYDROCHLORIDE
| storage temp. | 2-8°C |
| solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| form | Powder |
| Stability: | Hygroscopic |
Safety information for PROCATEROL HYDROCHLORIDE
Computed Descriptors for PROCATEROL HYDROCHLORIDE
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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