Potassium orotate

Synonym(s):6-Carboxy-2,4-dihydroxypyrimidine;Uracil-6-carboxylic acid

CAS NO.：24598-73-0
Empirical Formula: C5H3KN2O4
Molecular Weight: 194.19
MDL number: MFCD00039118
EINECS: 246-341-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-01 18:09:03

What is Potassium orotate?

The Uses of Potassium orotate

Orotic acid (OA) is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.

What are the applications of Application

Orotic acid potassium salt is an intermediate in pyrimidine biosynthesis

Properties of Potassium orotate

Melting point:	>300°C
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	Aqueous Base (Slightly)
form	Solid
color	White to Light Yellow
Stability:	Hygroscopic
CAS DataBase Reference	24598-73-0(CAS DataBase Reference)
EPA Substance Registry System	4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, monopotassium salt (24598-73-0)