Polaprezinc

Description

Polaprezinc, a complex of zinc ion and L-carnosine, is an antiulcer agent launched in Japan. It is effective in promoting the healing of gastric ulcers in addition to preventing ulcer relapse. In rat studies, polaprezinc reduces the incidence of stomach lesions induced by ethanol. No effect was seen on ultrastructural damage or on cell proliferation and it appears that polaprezinc combines the cytoprotective effect of zinc with the ulcer healing properties of Lcarnosine. The in vivo antioxidative properties of polaprezinc has been suggested to be responsible for its protective effect against gastric mucosal injury.
Recent studies revealed that polaprezinc is an activator of bone formetion and has inhibitory effect of bone resorption. This agent is thus able to prevent the deterioration of bone metabolism indicating its potential usefulness in the treatment of osteoporosis. Polaprezinc has also been claimed for the prophylaxis and treatment of alcoholic hepatopathy, viral hepatitis or other hepatopathies caused by certain drugs, poisons and radiation.

Chemical properties

White To Pale-Yellow Crystalline Solid

Originator

Hamari Chemicals (Japan)

The Uses of Polaprezinc

A novel anti-gastric ulcer agent

The Uses of Polaprezinc

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The Uses of Polaprezinc

anti-ulcer drug, antioxidative,

What are the applications of Application

Polaprezinc is An anti-gastric ulcer agent

brand name

Promac