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HomeProduct name listPlatycodin D2

Platycodin D2

Platycodin D2 Structural

What is Platycodin D2?

Description

Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses. Polygalacin D2 has anti-cancer activity, it exhibits significant inhibition on the proliferation of five kinds of cultured human tumor cell lines.

Definition

ChEBI: Platycodin D2 is a triterpenoid saponin. It has a role as a metabolite.

Biological Activity

Platycodin D2 is a saponin isolated from Platycodon grandiflorum, with anti-cancer activity.

in vitro

A novel triterpenoid saponin, deapioplatycoside Ewas isolated from the root extract of Platycodon grandiflorum, together with the seven known saponins 2 - 8, i. e., platycoside E, deapioplatycodin D3 , platycodin D3, polygalacin D2, Platycodin D2 , deapioplatycodin D and platycodin D. The structure of the new saponin 1 was determined on the basis of spectral analysis and chemical evidence.

Properties of Platycodin D2

Density  1.60±0.1 g/cm3 (20 ºC 760 Torr)
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Powder
pka 12.70±0.70(Predicted)
color  Off-white to light yellow

Safety information for Platycodin D2

Computed Descriptors for Platycodin D2

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