Pirarubicin
Synonym(s):THP
- CAS NO.：72496-41-4
- Empirical Formula: C32H37NO12
- Molecular Weight: 627.64
- MDL number: MFCD00869742
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-03 17:51:04
What is Pirarubicin?
Description
Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting.
Chemical properties
Red Solid
Originator
Meiji Seika (Japan)
The Uses of Pirarubicin
Structural analog of Doxorubicin. Antineoplastic
The Uses of Pirarubicin
Structural analog of Doxorubicin. Antineoplastic.
What are the applications of Application
Pirarubicin is an anti-neoplastic and inhibitor of Topo II
Definition
ChEBI: (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione is an anthracycline.
brand name
Pinorubicin; Therarubucin
Properties of Pirarubicin
| Melting point: | 188-192°C (dec.) |
| Boiling point: | 834.7±65.0 °C(Predicted) |
| alpha | D25 +175 ±25° (c = 0.2 in CHCl3) |
| Density | 1.51±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ethanol: soluble25mg/mL |
| form | powder |
| pka | 7.35±0.60(Predicted) |
| color | Orange to Red |
| Stability: | Hygroscopic |
Safety information for Pirarubicin
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H340:Germ cell mutagenicity H350:Carcinogenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for Pirarubicin
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