Pirarubicin

Synonym(s):THP

CAS NO.：72496-41-4
Empirical Formula: C32H37NO12
Molecular Weight: 627.64
MDL number: MFCD00869742
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 20:33:22

What is Pirarubicin?

Description

Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting.

Chemical properties

Red Solid

Originator

Meiji Seika (Japan)

The Uses of Pirarubicin

Structural analog of Doxorubicin. Antineoplastic

The Uses of Pirarubicin

Structural analog of Doxorubicin. Antineoplastic.

What are the applications of Application

Pirarubicin is an anti-neoplastic and inhibitor of Topo II

Definition

ChEBI: (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione is an anthracycline.

brand name

Pinorubicin; Therarubucin

Properties of Pirarubicin

Melting point:	188-192°C (dec.)
Boiling point:	834.7±65.0 °C(Predicted)
alpha	D25 +175 ±25° (c = 0.2 in CHCl3)
Density	1.51±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	ethanol: soluble25mg/mL
form	powder
pka	7.35±0.60(Predicted)
color	Orange to Red
Stability:	Hygroscopic

Safety information for Pirarubicin

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H340:Germ cell mutagenicity H350:Carcinogenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..…