PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER

Synonym(s):mono-2-Ethylhexyl phthalate

CAS NO.：4376-20-9
Empirical Formula: C16H22O4
Molecular Weight: 278.34
MDL number: MFCD00041500
EINECS: 224-477-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 15:53:33

PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER Structural

What is PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER?

Chemical properties

Colorless Oil

The Uses of PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER

Phthalic acid mono-2-ethylhexyl ester can be used as a precursor:

To synthesize dioctyl phthalate, a widely used plasticizer, via esterification reaction with 2-ethylhexanol.
To prepare a fluorescent probe, 2-[[(3′,6′-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-5-yl)amino]carbonyl] 2-ethylhexyl benzoic acid ester, to detect toxic metabolite mono-2-ethylhexyl phthalate (MEHP).

The Uses of PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER

Phthalate metabolite, responsible for inducing apoptosis in germ and Sertoli cells by disrupting junction complexes.

What are the applications of Application

MEHP is a bioactive metabolite of DEHP

Definition

ChEBI: The mono(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.

General Description

Clear colorless to cloudy white viscous liquid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER may react exothermically with strong oxidizing agents. May also generate heat with caustic solutions. Flammable hydrgen is generated by mixing with alkali metals and hydrides. May be sensitive to prolonged exposure to light.

Fire Hazard

PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER is probably combustible.

Properties of PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER

Melting point:	25-27℃
Boiling point:	341.16°C (rough estimate)
Density	0,107 g/cm³
refractive index	n/D1.5051
Flash point:	>93 °C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	liquid (Colorless)
pka	3.37±0.36(Predicted)
color	Colourless to Off-White Oil to Low-Melting
BRN	3206630
EPA Substance Registry System	Mono(2-ethylhexyl) phthalate (4376-20-9)

Safety information for PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.