PHENYLMERCURIC NITRATE

CAS NO.：8003-05-2
Empirical Formula: C12H11Hg2NO4
Molecular Weight: 634.4
MDL number: MFCD00151098
EINECS: 620-403-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is PHENYLMERCURIC NITRATE?

Chemical properties

white powder

The Uses of PHENYLMERCURIC NITRATE

Pharmaceutic aid (antimicrobial). Tree wound dressing.

General Description

Phenylmercury nitrate is a mercury-based organic compound known to have antibacterial and antifungal activities. It is also used as a preservative for parenteral injections.

Clinical Use

Phenylmercuric nitrate is a mixture of phenylmercuric nitrateand phenylmercuric hydroxide. It occurs as a whitecrystalline material that is sparingly soluble in water andslightly soluble in alcohol. It is used in concentrations of1:10,000 to 1:50,000 to preserve injectable drugs againstbacterial contamination. A disadvantage to organomercurialsis that their bacteriostatic efficacy is reduced in the presenceof serum.

Purification Methods

When recrystallised from water or aqueous EtOH, it has m 191-191.5o, and from 95% EtOH it has m 186.5o [Challanger & Rothstein J Chem Soc I 1258 1934]. When recrystallised from *C6H6 or CHCl3, it has m 131-131.5o [Morton et al. J Am Chem Soc 69 908 1947.] [Beilstein 16 III 1348, 16 IV 1721.]

Properties of PHENYLMERCURIC NITRATE

Melting point:	175-185 °C (dec.) (lit.)
vapor pressure	0.0000019 hPa at 20°C
storage temp.	Store below +30°C.
form	Solid
color	White crystalline
PH Range	6.6
Water Solubility	soluble ~1250 parts H2O; slightly soluble alcohol [MER06]
Merck	14,7302
CAS DataBase Reference	8003-05-2(CAS DataBase Reference)

Safety information for PHENYLMERCURIC NITRATE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H301:Acute toxicity,oral H314:Skin corrosion/irritation H372:Specific target organ toxicity, repeated exposure H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..…