PHENCYCLIDINE HYDROCHLORIDE
Synonym(s):1-(1-Phenylcyclohexyl)piperidine hydrochloride;PCP hydrochloride
- CAS NO.:956-90-1
- Empirical Formula: C17H26ClN
- Molecular Weight: 279.85
- MDL number: MFCD00058208
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is PHENCYCLIDINE HYDROCHLORIDE?
Chemical properties
Crystalline Solid
The Uses of PHENCYCLIDINE HYDROCHLORIDE
Controlled substance (depressant). Anesthetic (intravenous).
The Uses of PHENCYCLIDINE HYDROCHLORIDE
Anesthetic (intravenous). Controlled substance (depressant).
brand name
Sernylan (Parke-Davis).
Biological Activity
Non-competitive NMDA receptor antagonist and sigma receptor agonist. Psychostimulant; induces rotational behavior, head-weaving and cognitive dysfunction in rats.
Biochem/physiol Actions
σ opioid receptor agonist and psychostimulant; inhibits NMDA glutamate receptor activation by binding to an allosteric site within the ion channel.
Safety Profile
Poison by ingestion,subcutaneous, intravenous, and intraperitoneal routes.Human systemic effects by ingestion and intravenousroutes: distorted perceptions, euphoria, excitement,hallucinations, and paresthesia. An experimental teratogen.Other experime
storage
Store at RT
Properties of PHENCYCLIDINE HYDROCHLORIDE
Melting point: | 233-235°C |
Boiling point: | 135-137°C |
storage temp. | Store at RT |
solubility | H2O: 11.2 mg/mL |
form | Solid |
color | Crystals |
Water Solubility | Soluble to 40 mM in water |
EPA Substance Registry System | Piperidine, 1-(1-phenylcyclohexyl)-, hydrochloride (956-90-1) |
Safety information for PHENCYCLIDINE HYDROCHLORIDE
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral H336:Specific target organ toxicity,single exposure; Narcotic effects |
Computed Descriptors for PHENCYCLIDINE HYDROCHLORIDE
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