PHA-793887
- CAS NO.：718630-59-2
- Empirical Formula: C19H31N5O2
- Molecular Weight: 361.48
- MDL number: MFCD17169992
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is PHA-793887?
Chemical properties
White to Off-White Solid
The Uses of PHA-793887
PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors.
What are the applications of Application
PHA-793887 is a novel pan-Cdk inhibitor inactive against 34 other kinases
Definition
ChEBI: N-[6,6-dimethyl-5-[(1-methyl-4-piperidinyl)-oxomethyl]-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-methylbutanamide is a piperidinecarboxamide.
Properties of PHA-793887
| Melting point: | >147°C (dec.) |
| Boiling point: | 596.2±50.0 °C(Predicted) |
| Density | 1.176±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | DMSO (Slightly), Methanol(Slightly) |
| form | Solid |
| pka | 13.74±0.40(Predicted) |
| color | Off-White to Pale Yellow |
| Stability: | Hygroscopic |
Safety information for PHA-793887
Computed Descriptors for PHA-793887
New Products
4-Fluorophenylacetic acid (S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid 5-Aminoimidazole-4-Carbonitrile 4-chloro-3,5-dinitropyridine 2'-Methoxy-biphenyl-2-carboxaldehyde 2-(2-Aminoethyl)isothiourea dihydrobromide, 1-(4-chlorophenyl)propan-1-one 2-Ethyl-4-methyl-1-pentanol DIISOPROPYL MALONATE PENTAFLUOROPHENOL 2-Aminonicotinic acid 6-(4-AMINOPHENYL)-5-METHYL-4,5-DIHYDRO-3(2 H)-PYRDAZINONE β-BUTYROLACTONE 3-OXO-CYCLOBUTANECARBOXYLIC ACID 3-methyl xanthine 1H-Pyrazole-3-carboxylic acid [1,1'-Biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-hexahydro-2-oxo-4-[(1E)-3-oxo-4-[3- (trifluoromethyl)phenoxy]-1-buten-1-yl]-2H-cyclopenta[b]furan-5-yl ester 2H-Cyclopenta[b]furan-2,5-diol, hexahydro-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1- buten-1-yl]-, (3aR,4R,5R,6aS)- 2,5-Dibromopyridine Dimethyl (2-oxo-4-phenylbutyl)phosphonate S-(2-Chloro-3-nitrophenyl) O-ethyl carbonodithioate 1-Methyl-6-oxo-1,6-dihydropyridazine-3-carboxylic acid 2,4-Dichloro-1-[2-nitro-4-(trifluoromethyl)phenoxy]benzeneRelated products of tetrahydrofuran
![(2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol](https://img.chemicalbook.in/CAS/GIF/779353-01-4.gif)
You may like
-
PHA-793887 98% (HPLC) CAS 718630-59-2View Details
718630-59-2 -
108-12-3 99%View Details
108-12-3 -
102-27-2 N-Ethyl-m-toluidine (MEMT) 99%View Details
102-27-2 -
(3R,4R)-1-benzyl-N,4- dimethylpiperidin-3-amine 477600-70-7 99%View Details
477600-70-7 -
L-tert-Leucine 99%View Details
20859-02-3 -
372-18-9 99%View Details
372-18-9 -
Ortho Phenylene Diamine (OPDA) 95-54-5 99%View Details
95-54-5 -
77-78-1 99%View Details
77-78-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.