PENTAETHYLENEHEXAMINE

Synonym(s):3,6,9,12-Tetraazatetradecane-1,14-diamine;Pentaethylenehexamine

CAS NO.：4067-16-7
Empirical Formula: C10H28N6
Molecular Weight: 232.37
MDL number: MFCD00008167
EINECS: 223-775-9
SAFETY DATA SHEET (SDS)
Update Date: 2023-09-26 09:42:43

What is PENTAETHYLENEHEXAMINE?

Chemical properties

dark yellow-green liquid

The Uses of PENTAETHYLENEHEXAMINE

5.Pentaethylenehexamine has been used in the preparation of:

polyisobutylene succinimide (PIBSI) dispersants, used as engine oil-additives
poly(glycidyl methacrylate) (P(GMA)) homopolymers
poly(amidoamine)s

What are the applications of Application

Pentaethylenehexamine is a versatile polyamine synthesis reagent

General Description

Yellowish liquid with an odor of ammonia.

Air & Water Reactions

Water soluble.

Reactivity Profile

PENTAETHYLENEHEXAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

Contact with eyes can cause slight to moderate irritation and possible burns. May cause transient fogging of the eyes as a result of corneal edema, which is reversible. May cause moderate skin irritation or allergic skin reaction with symptoms of redness, itching, swelling, or rash. Vapors may irritate the eyes, nose, throat, and respiratory tract. May cause coughing, headache, nausea and vomiting. If swallowed, may cause nausea, vomiting and abdominal pain. May cause burns of the mouth, throat, esophagus, and stomach.

Safety Profile

Moderately toxic by ingestion. Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.

Purification Methods

Fractionally distil it twice at 10-20mm, the fraction boiling at 220-250o being collected. It can be further purified via the hydrochloride. Its solution in MeOH (40mL of base in 250mL) is cooled in an ice-bath and conc HCl (~50mL) is added dropwise with stirring. The precipitated hydrochloride is filtered off, washed with Me2CO, and Et2O, then dried in a vacuum desiccator. The free base is then obtained by basification, extraction into Et2O, drying (NaOH), filtering, evaporating and distilling the residue as before. It forms a Cu complex [Cu(C10H28N6)]2+. [Jonassen et al. J Am Chem Soc 79 4279 1957, Beilstein 4 IV 1245.]

Properties of PENTAETHYLENEHEXAMINE

Melting point:	-35 °C
Boiling point:	380 °C
Density	0.95 g/mL at 25 °C (lit.)
vapor pressure	<1 hPa (20 °C)
refractive index	n20/D 1.5096(lit.)
Flash point:	>230 °F
storage temp.	Store below +30°C.
solubility	water: soluble500g/L at 20°C
form	Liquid
pka	10.07±0.19(Predicted)
color	Clear yellow
PH	11 (10g/l, H2O)
BRN	1768042
Stability:	Stable. Incompatible with strong oxidizing agents, strong acids.
CAS DataBase Reference	4067-16-7(CAS DataBase Reference)
EPA Substance Registry System	Pentaethylenehexamine (4067-16-7)

Safety information for PENTAETHYLENEHEXAMINE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H314:Skin corrosion/irritation H317:Sensitisation, Skin H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.