Pentachloropyridine

Synonym(s):Pentachloropyridine;Perchloropyridine

CAS NO.：2176-62-7
Empirical Formula: C5Cl5N
Molecular Weight: 251.33
MDL number: MFCD00006230
EINECS: 218-535-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-30 18:52:02

What is Pentachloropyridine?

Description

Pentachloropyridine is one of the most important perhalogenated compounds which find broad applications in many fields of chemistry. It is most reactive at the 4- position. Reduction with zinc, or electrochemically, yields 2,3,5,6-tetrachloropyridine. Partial hydrolysis and phosphorylation gives the insecticide chlorpyrifos.

Chemical properties

WHITE TO OFF-WHITE FLAKES

The Uses of Pentachloropyridine

Pentachloropyridine is a halogenated pyridine with antineoplastic and antiapoptic properties.

What are the applications of Application

Pentachloropyridine is a halogenated pyridine with antineoplastic and antiapoptic properties

Preparation

Pentachloropyridine can be produced through a direct electrophilic substitution reaction between pyridine and chlorine.

Safety Profile

Poison by intraperitoneal route. When heated to decomposition it emits very toxic fumes of Clí and NOx.

Purification Methods

Purify it by recrystallisation from EtOH or aqueous EtOH. It sublimes at 150o/3mm. [den Hertog et al. Recl Trav Chim Pays-Bas 69 673 1950, Schikh et al. Chem Ber 69 2604 1936, Beilstein 20 I 81, 20 III/IV 2503, 20/5 V 422.]

Properties of Pentachloropyridine

Melting point:	124 °C
Boiling point:	280 °C
Density	1.7500 (estimate)
vapor density	8.4 (vs air)
vapor pressure	0.01 mm Hg ( 20 °C)
storage temp.	Store below +30°C.
solubility	9mg/l
form	Flakes
pka	-6.23±0.50(Predicted)
color	White to off-white
BRN	155197
CAS DataBase Reference	2176-62-7(CAS DataBase Reference)
NIST Chemistry Reference	Pyridine, pentachloro-(2176-62-7)
EPA Substance Registry System	Pyridine, pentachloro- (2176-62-7)

Safety information for Pentachloropyridine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P391:Collect spillage. Hazardous to the aquatic environment P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..…