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Olivomycin

Olivomycin Structural

What is Olivomycin?

Definition

ChEBI: Olivomycin A is an olivomycin and a secondary alpha-hydroxy ketone. It has a role as an antimicrobial agent.

Safety Profile

Poison by intraperitoneal andintravenous routes.

Enzyme inhibitor

These chromomycin-like antibiotics (FWOlivomycin-A = 1197.3 g/mol; CAS 6988-58-5) produced by Streptomyces olivoreticuli anthat bind to DNA in a base pair-specific manner, preferring Guanine:Cytosine pairs. The major component, olivimycin A, is a yellow solid that is insoluble in water and soluble in ethanol and chloroform. Target(s): DNA-directed DNA polymerase; DNA-directed RNA polymerase; EcoRI restriction endonuclease, or Type II site-specific deoxyribonuclease.

Properties of Olivomycin

Melting point: 160-165°
Boiling point: 782.67°C (rough estimate)
alpha  D20 -36° (c = 0.5 in ethanol)
Density  1.1373 (rough estimate)
refractive index  1.6500 (estimate)
pka 4.36±0.60(Predicted)
color  Yellow crystals

Safety information for Olivomycin

Computed Descriptors for Olivomycin

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