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HomeProduct name listNU6140

NU6140

NU6140 Structural

What is NU6140?

The Uses of NU6140

NU 6140 is a cyclin-dependant kinase 2 inhibitor which demonstrates 10-36 fold selectivity against Cdk2-cyclin A. This selectivity induces cell-cycle arrest at the G2-M phase and potentiates the apoptotic effect of pacitaxel.

What are the applications of Application

NU 6140 is a highly cell-permeable purine compound that acts a ATP-competitive inhibitor of Cdks

storage

Desiccate at +4°C

Properties of NU6140

Boiling point: 707.8±70.0 °C(Predicted)
Density  1.234±0.06 g/cm3(Predicted)
storage temp.  Desiccate at +4°C
solubility  DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
form  White to off-white solid.
pka 9.41±0.10(Predicted)
color  White to light yellow

Safety information for NU6140

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for NU6140

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