NU6140
- CAS NO.：444723-13-1
- Empirical Formula: C23H30N6O2
- Molecular Weight: 422.52
- MDL number: MFCD09264153
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 14:32:37
What is NU6140?
The Uses of NU6140
NU 6140 is a cyclin-dependant kinase 2 inhibitor which demonstrates 10-36 fold selectivity against Cdk2-cyclin A. This selectivity induces cell-cycle arrest at the G2-M phase and potentiates the apoptotic effect of pacitaxel.
What are the applications of Application
NU 6140 is a highly cell-permeable purine compound that acts a ATP-competitive inhibitor of Cdks
storage
Desiccate at +4°C
Properties of NU6140
| Boiling point: | 707.8±70.0 °C(Predicted) |
| Density | 1.234±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at +4°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml |
| form | White to off-white solid. |
| pka | 9.41±0.10(Predicted) |
| color | White to light yellow |
Safety information for NU6140
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for NU6140
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