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HomeProduct name listNodinitib-1

Nodinitib-1

Synonym(s):1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-amine;CID-1088438;ML130

Nodinitib-1 Structural

What is Nodinitib-1?

The Uses of Nodinitib-1

Noditinib-1 is a potent and selective inhibitor of NOD1-induced NF-κB activation. Mutations in NOD proteins have been associated with various inflammatory diseases and Noditinib-1 shows promise as a potential therapeutic agent.

Definition

ChEBI: 1-(4-methylphenyl)sulfonyl-2-benzimidazolamine is a sulfonamide.

Properties of Nodinitib-1

Melting point: 191-192 °C (decomp)
Boiling point: 532.5±43.0 °C(Predicted)
Density  1.40±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,2-8°C
solubility  DMSO: >10mg/mL
form  powder
pka 2.55±0.10(Predicted)
color  white to beige

Safety information for Nodinitib-1

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Nodinitib-1

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