NIPECOTAMIDE
Synonym(s):3-Carbamoylpiperidine;3-Piperidinecarboxamide
- CAS NO.:4138-26-5
- Empirical Formula: C6H12N2O
- Molecular Weight: 128.17
- MDL number: MFCD00005993
- EINECS: 223-962-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-18 08:51:57
What is NIPECOTAMIDE?
Chemical properties
YELLOW CRYSTALLINE POWDER
The Uses of NIPECOTAMIDE
Nipecotamide, is a budiling blcok used in the sythnesis of various compounds, such as DPP-4 inhibitors, IKKβ inhibitors, piroimidazolidinone NPC1L1 inhibitors, and Anti-HIV agents.
The Uses of NIPECOTAMIDE
Reactant for synthesis of:• ;DPP-4 inhibitors1• ;IKKβ inhibitors2• ;Spiroimidazolidinone NPC1L1 inhibitors3• ;Sulfamides4• ;Phosphodiesterase 5 inhibtors5• ;Anti-HIV agents6
Definition
ChEBI: The amide resulting from the formal condensation of nipecotic acid with ammonia.
Properties of NIPECOTAMIDE
Melting point: | 103-106 °C(lit.) |
Boiling point: | 237.61°C (rough estimate) |
Density | 1.0754 (rough estimate) |
refractive index | 1.4880 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
pka | 16.50±0.20(Predicted) |
form | Crystalline Powder |
color | Yellow |
CAS DataBase Reference | 4138-26-5(CAS DataBase Reference) |
Safety information for NIPECOTAMIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for NIPECOTAMIDE
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
DIHYDROERGOCRISTINE MESYLATE
N,N-DIETHYLNIPECOTAMIDE
dihydroergocristine
Rispenzepine
DIHYDROERGOTAMINE MESYLATE
2-OXO-PIPERIDINE-3-CARBOXYLIC ACID (2-AMINO-ETHYL)-AMIDE
Desocriptine
Dihydro α-Ergocryptine
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