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HomeProduct name listNicosulfuron

Nicosulfuron

Synonym(s):1-(4,6-Dimethoxy-2-pyrimidinyl)-3-[3-(dimethylcarbamoyl)-2-pyridylsulfonyl]urea;2-[(4,6-Dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-N,N-dimethylnicotinamide

  • CAS NO.:111991-09-4
  • Empirical Formula: C15H18N6O6S
  • Molecular Weight: 410.4
  • MDL number: MFCD00203303
  • EINECS: 244-666-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-13 11:39:26
Nicosulfuron Structural

What is Nicosulfuron?

Chemical properties

White Solid

Chemical properties

White crystalline solid or powder. Phenolic odor.

The Uses of Nicosulfuron

Herbicide.

The Uses of Nicosulfuron

Post-emergence sulfonylurea herbicide

Definition

ChEBI: A N-sulfonylurea that is 2-(carbamoylsulfamoyl)-N,N-dimethylpyridine-3-carboxamide substituted by a 4,6-dimethoxypyrimidin-2-yl group at the amino nitrogen.

Agricultural Uses

Herbicide: Used as a post-emergence herbicide to control a variety of weeds on field corn and popcorn crops. Some formulations may be U.S. EPA restricted Use Pesticides (RUP). Approved for use in EU countries.

Trade name

ACCENT®; BASIS®; CELEBRITY®; CHALLENGER®; DASUL®; DPX 79406® Herbicide (with Rimsulfuron); DPX-V9636®; GHIBLI®; LAMA®; MATRIX® Herbicide (with Rimsulfuron); MILAGRO®; MISTRAL®; MOTIVEL®; NISSHIN®; SAMSON®; STEADFAST® (nicosulfuron + rimsulfuron)

Potential Exposure

Nicosulfuron is a sulfonylurea postemergence herbicide used to control a variety of weeds on field corn and popcorn crops. Some formulations may be registered as United States Restricted Use Pesticides (RUP)

Metabolic pathway

In the four systems investigated, the primary degradation pathway is to yield pyridine sulfonamide and 4,6-dimethoxy-2-aminopyrimidine. The plant and its microsomal system include the hydroxylation pathway at the 4-position of the pyrimidine ring, resulting in hydrolysis products by the cleavage of the sulfonylurea linkage. In mammals, contraction or rearrangement of the sulfonylurea linkage for nicosulfuron and N- demethylated nicosulfuron yields two unique products which have the N-pyridyl-N-pyrimidyl urea moiety and result in the uracil metabolite.

Shipping

UN3077 or UN3082 Environmentally hazardous substances, liquid or solid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Incompatibilities

Slowly hydrolyzes in water, releasing ammonia and forming acetate salts. Decomposed >165℃.

Waste Disposal

It is the responsibility of chemical waste generators to determine the toxicity and physical properties and of a discarded chemical and to properly identify its classification and certification as a hazardous waste and to determine the disposal method. United States Environmental Protection Agency guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult and follow all regional, national, state and local hazardous waste laws to ensure complete and accurate classification and disposal methods.

Properties of Nicosulfuron

Melting point: 141-144°C
Density  1.4126 (rough estimate)
refractive index  1.7000 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO: 50 mg/mL (121.83 mM)
form  neat
pka pKa (25°): 4.6
form  Solid
color  White to off-white
Stability: Hygroscopic, Unstable in DMSO
CAS DataBase Reference 111991-09-4(CAS DataBase Reference)
EPA Substance Registry System Nicosulfuron (111991-09-4)

Safety information for Nicosulfuron

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P273:Avoid release to the environment.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Nicosulfuron

InChIKey RTCOGUMHFFWOJV-UHFFFAOYSA-N

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