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HomeProduct name listNicomol

Nicomol

  • CAS NO.:27959-26-8
  • Empirical Formula: C34H32N4O9
  • Molecular Weight: 640.63928
  • MDL number: MFCD00865754
  • EINECS: 2487489
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 23:16:16
Nicomol Structural

What is Nicomol?

Originator

Cholexamine,Kyorin,Japan,1971

Definition

ChEBI: Nicomol is an organic molecular entity.

Manufacturing Process

To a mixture of 60 cc of benzene, 40 cc of pyridine and 17 g of hydrochloric acid salt of nicotinic acid chloride, was added 4.5 g of 2,2,6,6- tetramethylolcyclohexanol, and the whole mixture was refuxed at 75°C to 80°C for 2.5 hours. After the mixture was cooled water was added. Precipitate formed was separated by filtration, washed thoroughly with water and dried. Recrystallization from dilute acetic acid gave 14 g of the final compound, melting point 177°C to 180°C.

Therapeutic Function

Anticholesteremic

Properties of Nicomol

Melting point: 177-180°
Boiling point: 672.42°C (rough estimate)
Density  1.3015 (rough estimate)
refractive index  1.6000 (estimate)
storage temp.  2-8°C
pka 13.53±0.60(Predicted)
form  Solid
color  White to off-white

Safety information for Nicomol

Computed Descriptors for Nicomol

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