Nicomol
- CAS NO.：27959-26-8
- Empirical Formula: C34H32N4O9
- Molecular Weight: 640.63928
- MDL number: MFCD00865754
- EINECS: 2487489
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:58
What is Nicomol?
Originator
Cholexamine,Kyorin,Japan,1971
Definition
ChEBI: Nicomol is an organic molecular entity.
Manufacturing Process
To a mixture of 60 cc of benzene, 40 cc of pyridine and 17 g of hydrochloric acid salt of nicotinic acid chloride, was added 4.5 g of 2,2,6,6- tetramethylolcyclohexanol, and the whole mixture was refuxed at 75°C to 80°C for 2.5 hours. After the mixture was cooled water was added. Precipitate formed was separated by filtration, washed thoroughly with water and dried. Recrystallization from dilute acetic acid gave 14 g of the final compound, melting point 177°C to 180°C.
Therapeutic Function
Anticholesteremic
Properties of Nicomol
| Melting point: | 177-180° |
| Boiling point: | 672.42°C (rough estimate) |
| Density | 1.3015 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | 2-8°C |
| pka | 13.53±0.60(Predicted) |
| form | Solid |
| color | White to off-white |
Safety information for Nicomol
Computed Descriptors for Nicomol
New Products
Tubulysin E Tubulysin H Tubulysin B Tubulysin G tetrahydro-4-methyl-2H-pyran 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate CYCLOBUTYLAMINE HYDROCHLORIDE 3-METHYLAZETIDIN-3-OL HYDROCHLORIDE 1-(1,1-Difluoroethyl)-2-fluorobenzene 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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