NEBULARINE
- CAS NO.：550-33-4
- Empirical Formula: C10H12N4O4
- Molecular Weight: 252.23
- MDL number: MFCD00022819
- EINECS: 208-981-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-08 20:21:46
What is NEBULARINE?
Description
This purine base is produced by Agarius nebularis Batsch. (Syn. Clitocybe nebularis). It is laevorotatory with [α]25D - 48.6° (c 1.0, H20).
Chemical properties
Crystalline Solid
The Uses of NEBULARINE
Nebularine is shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria.
What are the applications of Application
Nebularine is a purine nucleoside
Definition
ChEBI: A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage.
storage
+4°C
Purification Methods
Nebularine is recrystallised from butanone/MeOH or EtOH and forms a MeOH photo-adduct. It is a strong inhibitor of adenosine deaminase [EC 3.5.4.4]. [Nair & Weichert Bioorg Chem 9 423 1980, Lfgren et al. Acta Chem Scand 7 225 1953, UV: Brown & Weliky J Biol Chem 204 1019 1953, Beilstein 26 III/IV 1740.]
Properties of NEBULARINE
| Melting point: | 181-182°C |
| Boiling point: | 395.4°C (rough estimate) |
| alpha | D25 -48.6° (H2O) |
| Density | 1.3402 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Ethanol, Methanol (Slightly) |
| form | Solid |
| pka | 13.13±0.70(Predicted) |
| color | Pale Beige to Beige |
| Merck | 13,6461 |
| Stability: | Hygroscopic |
Safety information for NEBULARINE
Computed Descriptors for NEBULARINE
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION XANTHAN GUM Racecadotril SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN Folic Acid Impurity G Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
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