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HomeProduct name list6-THIOGUANOSINE

6-THIOGUANOSINE

  • CAS NO.:85-31-4
  • Empirical Formula: C10H13N5O4S
  • Molecular Weight: 299.31
  • MDL number: MFCD00005736
  • EINECS: 201-597-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-11 17:44:06
6-THIOGUANOSINE Structural

What is 6-THIOGUANOSINE?

Chemical properties

Tan Powder

The Uses of 6-THIOGUANOSINE

antineoplastic

Definition

ChEBI: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-3H-purine-6-thione is a purine nucleoside.

Purification Methods

Thioguanosine is crystallised (as hemihydrate) from hot H2O (charcoal) and cooled slowly to give tapered prisms. It also crystallises by dissolving in dilute NH3 and acidifying with acetic acid, and then recrystallising from H2O. UV: (pH 4-6) max at 257nm ( 8,820) and 342nm ( 24,800), and (pH 10.4-12.0) max at 252nm ( 14,700) and 319.5nm ( 21,000). [Fox et al. J Am Chem Soc 80 1667 1958, Beilstein 26 III/IV 3927.]

Properties of 6-THIOGUANOSINE

Melting point: 230-231°C
Boiling point: 756.9±70.0 °C(Predicted)
Density  2.18
refractive index  1.6460 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka 13.21±0.70(Predicted)
form  Solid
color  Off-white to light yellow
CAS DataBase Reference 85-31-4(CAS DataBase Reference)

Safety information for 6-THIOGUANOSINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 6-THIOGUANOSINE

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