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HomeProduct name listNADP, Disodium Salt

NADP, Disodium Salt

Synonym(s):β-NADH phosphate disodium salt;β-NADP-Na2;β-Nicotinamide-adenine Dinucleotide Phosphate, TPN, 2Na;NADP disodium salt;Nicotinamide adenine dinucleotide phosphate disodium salt

  • CAS NO.:24292-60-2
  • Empirical Formula: C21H29N7NaO17P3
  • Molecular Weight: 767.41
  • MDL number: MFCD00065390
  • EINECS: 246-129-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-20 11:41:24
NADP, Disodium Salt Structural

What is NADP, Disodium Salt?

Description

NADP+ is a coenzyme that is widely distributed in living matter, Participates in oxidation-reduction reactions. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).
NADP is a substance in which nicotinic acid amide adenine dinucleotide and a phosphate molecule are bound by ester bond. It is a hydrogen receptor and can be used for the development and development of a variety of in vitro diagnostic reagents. Prepared in large quantities.
NADP

Chemical properties

Yellowish powder

The Uses of NADP, Disodium Salt

Disodium NADP is used in method for preparing 2,4-Diamino Butyric Acid by enzyme catalysis.

The Uses of NADP, Disodium Salt

Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.

What are the applications of Application

NADP, Disodium Salt is a participant coenzyme in aerobic and anaerobic oxidation

What are the applications of Application

A participant coenzyme in aerobic and anaerobic oxidation
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.

General Description

Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo.

Biotechnological Applications

Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo. The β-NADH phosphate disodium salt has been used for the quantification of glucose in glycogen. It has also been used for the hexokinase assay.

Mechanism of action

β-Nicotinamide adenine dinucleotide NAD and β-nicotinamide adenine dinucleotide phosphate NADP are coenzymes necessary for cellular energy metabolism and play a central role in energy metabolism. In addition, purine nucleotides also play an important transfer role in biological processes. Protons in energy reactions are usually first transferred to NAD and NADP, then reduced to NADH and NADPH, and transferred to oxygen through electrons to release energy. The generated reduced NADH and NADPH are coenzymes of glutathione reductase and have important antioxidant functions.

Precautions

Protect from light and moisture. Keep cool and dry. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Store under inert gas.

Properties of NADP, Disodium Salt

Melting point: 175-178 °C
Density  1.66g/cm3 at 20℃
vapor pressure  0.002-0.004Pa at 20-25℃
storage temp.  -20°C
solubility  DMSO (Slightly), Water (Slightly)
form  Powder
color  Yellow
PH 4.0 ± 1.0(10mg/mL)
Odor Odorless
Water Solubility  >50 g/L
Stability: Hygroscopic
CAS DataBase Reference 24292-60-2

Safety information for NADP, Disodium Salt

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H227:Flammable liquids
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.
P370+P378:In case of fire: Use … for extinction.
P403+P235:Store in a well-ventilated place. Keep cool.

Computed Descriptors for NADP, Disodium Salt

InChIKey UNRRSQIQTVFDLS-WUEGHLCSSA-L

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