NADP, Disodium Salt
Synonym(s):β-NADH phosphate disodium salt;β-NADP-Na2;β-Nicotinamide-adenine Dinucleotide Phosphate, TPN, 2Na;NADP disodium salt;Nicotinamide adenine dinucleotide phosphate disodium salt
- CAS NO.:24292-60-2
- Empirical Formula: C21H29N7NaO17P3
- Molecular Weight: 767.41
- MDL number: MFCD00065390
- EINECS: 246-129-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 11:41:24
What is NADP, Disodium Salt?
Description
NADP+ is a coenzyme that is widely distributed in living matter, Participates in oxidation-reduction reactions. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).
NADP is a substance in which nicotinic acid amide adenine dinucleotide and a phosphate molecule are bound by ester bond. It is a hydrogen receptor and can be used for the development and development of a variety of in vitro diagnostic reagents. Prepared in large quantities.
Chemical properties
Yellowish powder
The Uses of NADP, Disodium Salt
Disodium NADP is used in method for preparing 2,4-Diamino Butyric Acid by enzyme catalysis.
The Uses of NADP, Disodium Salt
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.
What are the applications of Application
NADP, Disodium Salt is a participant coenzyme in aerobic and anaerobic oxidation
What are the applications of Application
A participant coenzyme in aerobic and anaerobic oxidation
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.
General Description
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo.
Biotechnological Applications
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo. The β-NADH phosphate disodium salt has been used for the quantification of glucose in glycogen. It has also been used for the hexokinase assay.
Mechanism of action
β-Nicotinamide adenine dinucleotide NAD and β-nicotinamide adenine dinucleotide phosphate NADP are coenzymes necessary for cellular energy metabolism and play a central role in energy metabolism. In addition, purine nucleotides also play an important transfer role in biological processes. Protons in energy reactions are usually first transferred to NAD and NADP, then reduced to NADH and NADPH, and transferred to oxygen through electrons to release energy. The generated reduced NADH and NADPH are coenzymes of glutathione reductase and have important antioxidant functions.
Precautions
Protect from light and moisture. Keep cool and dry. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Store under inert gas.
Properties of NADP, Disodium Salt
Melting point: | 175-178 °C |
Density | 1.66g/cm3 at 20℃ |
vapor pressure | 0.002-0.004Pa at 20-25℃ |
storage temp. | -20°C |
solubility | DMSO (Slightly), Water (Slightly) |
form | Powder |
color | Yellow |
PH | 4.0 ± 1.0(10mg/mL) |
Odor | Odorless |
Water Solubility | >50 g/L |
Stability: | Hygroscopic |
CAS DataBase Reference | 24292-60-2 |
Safety information for NADP, Disodium Salt
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for NADP, Disodium Salt
InChIKey | UNRRSQIQTVFDLS-WUEGHLCSSA-L |
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