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HomeProduct name listNε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester

Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester

Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester Structural

What is Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester?

Description

Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester is a PEG ligand, a synthetic side chain of liraglutide, a peptide drug used in the treatment of type 2 diabetes. It can also be used to prepare Glp-2 derivatives modified with lipophilic substituents.

Chemical properties

White crystalline powder

The Uses of Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester

Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester is used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles.

The Uses of Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester

Used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles. An antiobesity agent.

Properties of Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester

Melting point: 86.0 to 90.0 °C
Density  1.08±0.1 g/cm3(Predicted)
storage temp.  Hygroscopic, Refrigerator, Under Inert Atmosphere
solubility  Chloroform (Slightly), Methanol (Slightly, Heated)
form  Solid
pka 14.40±0.46(Predicted)
color  White to Pale Yellow
Stability: Sensitive to light, heat and humidity
CAS DataBase Reference 204521-63-1

Safety information for Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P362:Take off contaminated clothing and wash before reuse.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester

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