Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester
- CAS NO.:204521-63-1
- Empirical Formula: C29H50N2O7
- Molecular Weight: 538.72
- MDL number: MFCD22989465
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-26 15:15:06
What is Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester?
Description
Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester is a PEG ligand, a synthetic side chain of liraglutide, a peptide drug used in the treatment of type 2 diabetes. It can also be used to prepare Glp-2 derivatives modified with lipophilic substituents.
Chemical properties
White crystalline powder
The Uses of Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester
Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester is used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles.
The Uses of Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester
Used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles. An antiobesity agent.
Properties of Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester
Melting point: | 86.0 to 90.0 °C |
Density | 1.08±0.1 g/cm3(Predicted) |
storage temp. | Hygroscopic, Refrigerator, Under Inert Atmosphere |
solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
form | Solid |
pka | 14.40±0.46(Predicted) |
color | White to Pale Yellow |
Stability: | Sensitive to light, heat and humidity |
CAS DataBase Reference | 204521-63-1 |
Safety information for Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester
Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester manufacturer
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