N-ACETYLLACTOSAMINE
Synonym(s):β-D -Gal-(1→4)-D -GlcNAc;2-Acetamido-2-deoxy-4-O-β-D -galactopyranosyl-D -glucopyranose;LN;N-Acetyl-4-O-(β-D -galactopyranosyl)-D -glucosamine
- CAS NO.:32181-59-2
- Empirical Formula: C14H25NO11
- Molecular Weight: 383.35
- MDL number: MFCD00063785
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-28 13:53:26
What is N-ACETYLLACTOSAMINE?
Chemical properties
White Crystalline Solid
The Uses of N-ACETYLLACTOSAMINE
N-Acetyllactosamine is used in the expansion of a multi-funcational natural scaffold for the study of structural space of the Galectin-1-Ligand interaction. Also, it is used to identify the impurity as an imidazoline ring structure.
The Uses of N-ACETYLLACTOSAMINE
A component of oligosaccharide portion of many N- and O-linked glycoproteins. It is a building unit for the antigenic determinants of a number of certain human blood group activities as well as of the ABH Type 2 determinants
The Uses of N-ACETYLLACTOSAMINE
N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.
What are the applications of Application
N-Acetyl-D-lactosamine is a substrate of Sialyltransferase, FucT and Galactosidase
Definition
ChEBI: Beta-D-Galp-(1->4)-D-GlcpNAc is a disaccharide consisting of beta-D-galactose linked via a (1->4)-glycosidic bond to N-acetyl-D-glucosamine. It is a glucosamine oligosaccharide and a member of lactosamines.
Purification Methods
Purify N-acetyl-D-lactosamine by recrystallisation from MeOH (with 1 mol of MeOH) or from H2O. It is available commercially as a solution of 0.5g/mL of H2O. [Zilliken J Biol Chem 271 181 1955, Beilstein 17 IV 3452.]
Properties of N-ACETYLLACTOSAMINE
Melting point: | 191-192 |
Boiling point: | 858.1±65.0 °C(Predicted) |
Density | 1.58±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | H2O: 10 mg/mL, clear, colorless |
pka | 12.85±0.20(Predicted) |
form | Solid |
color | White to Pale Beige |
BRN | 96808 |
Stability: | Hygroscopic |
Safety information for N-ACETYLLACTOSAMINE
Computed Descriptors for N-ACETYLLACTOSAMINE
New Products
Tubulysin I (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride 2,2-diethoxyethanethioamide 3-N-BOC-(S)-AMINO BUTYRONITRILE Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 2H-Pyran, 4-ethynyltetrahydro- 4,4-DIFLUOROCYCLOHEXANAMINE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 7-chloro-1- (2-methyl-4- nitrobenzoyl)-3,4- dihydro-1H-benzo[b] azepin-5(2H)-one 5-Piperazin-1-yl- benzofuran-2- carboxylic acid ethyl ester. HCl Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate 7-Methoxyquinoline-4-carboxylic acid 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
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