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HomeProduct name listN-ACETYLLACTOSAMINE

N-ACETYLLACTOSAMINE

Synonym(s):β-D-Gal-(1→4)-D-GlcNAc;2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose;LN;N-Acetyl-4-O-(β-D-galactopyranosyl)-D-glucosamine

  • CAS NO.:32181-59-2
  • Empirical Formula: C14H25NO11
  • Molecular Weight: 383.35
  • MDL number: MFCD00063785
  • EINECS: 246-914-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-11 16:58:07
N-ACETYLLACTOSAMINE Structural

What is N-ACETYLLACTOSAMINE?

Chemical properties

White Crystalline Solid

The Uses of N-ACETYLLACTOSAMINE

N-Acetyllactosamine is used in the expansion of a multi-funcational natural scaffold for the study of structural space of the Galectin-1-Ligand interaction. Also, it is used to identify the impurity as an imidazoline ring structure.

The Uses of N-ACETYLLACTOSAMINE

A component of oligosaccharide portion of many N- and O-linked glycoproteins. It is a building unit for the antigenic determinants of a number of certain human blood group activities as well as of the ABH Type 2 determinants

The Uses of N-ACETYLLACTOSAMINE

N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.

What are the applications of Application

N-Acetyl-D-lactosamine is a substrate of Sialyltransferase, FucT and Galactosidase

Definition

ChEBI: Beta-D-Galp-(1->4)-D-GlcpNAc is a disaccharide consisting of beta-D-galactose linked via a (1->4)-glycosidic bond to N-acetyl-D-glucosamine. It is a glucosamine oligosaccharide and a member of lactosamines.

Purification Methods

Purify N-acetyl-D-lactosamine by recrystallisation from MeOH (with 1 mol of MeOH) or from H2O. It is available commercially as a solution of 0.5g/mL of H2O. [Zilliken J Biol Chem 271 181 1955, Beilstein 17 IV 3452.]

Properties of N-ACETYLLACTOSAMINE

Melting point: 191-192
Boiling point: 858.1±65.0 °C(Predicted)
Density  1.58±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  H2O: 10 mg/mL, clear, colorless
pka 12.85±0.20(Predicted)
form  Solid
color  White to Pale Beige
BRN  96808
Stability: Hygroscopic

Safety information for N-ACETYLLACTOSAMINE

Computed Descriptors for N-ACETYLLACTOSAMINE

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