N-OMEGA-METHYLSEROTONIN OXALATE SALT

Description

5-hydroxy-N^ω-methyl Tryptamine is a metabolite of serotonin (5-HT; ) in humans that has also been found in plants. It is an agonist of the 5-HT receptor subtype 5-HT₇ (IC₅₀ = 23 pM in a radioligand binding assay). 5-hydroxy-N^ω-methyl Tryptamine increases intracellular cyclic AMP production in HEK293 cells expressing 5-HT₇ (EC₅₀ = 22 nM). It inhibits serotonin uptake in HEK293 cells expressing human serotonin transporters (IC₅₀ = 490 nM). Elevated levels of urinary 5-hydroxy-N^ω-methyl tryptamine have been found in patients with schizophrenia, depression, and epilepsy.

What are the applications of Application

5-Hydroxy-Nω-methyltryptamine oxalate is reactant for preparation of 5-HT receptor agonists