2-mercapto-N-methylbenzamide
- CAS NO.：20054-45-9
- Empirical Formula: C8H9NOS
- Molecular Weight: 167.23
- MDL number: MFCD00136334
- EINECS: 633-825-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-05 12:01:54
What is 2-mercapto-N-methylbenzamide?
Description
N-methyl-2-sulfanylbenzamide is an axitinib intermediate.
The Uses of 2-mercapto-N-methylbenzamide
2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
What are the applications of Application
2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
Synthesis
2-mercapto-N-methylbenzamide is prepared by reactig 2,2'-Disulfanediylbis(N-methylbenzamide) and sodium tetrahydroborate In tetrahydrofuran.
Properties of 2-mercapto-N-methylbenzamide
| Melting point: | 94-96 °C |
| Boiling point: | 326.2±25.0 °C(Predicted) |
| Density | 1.174 |
| storage temp. | 2-8°C |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) |
| pka | 5.89±0.43(Predicted) |
| form | Solid |
| color | Off-White to Pale Beige |
| Stability: | Air Sensitive |
Safety information for 2-mercapto-N-methylbenzamide
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-mercapto-N-methylbenzamide
2-mercapto-N-methylbenzamide manufacturer
Riddhesh Pharmachem
1Y
Phone:+91-9106014993
Whatsapp: +91 9324548771
product: 2-Mercapto-N-methyl-benzamide 98%
Venkatasai Life Sciences
1Y
Phone:+91-8008303069
Whatsapp: +91 8008303069
product: 2-Mercapto-N-methyl-benzamide 20054-45-9 99%
Rivashaa Agrotech Biopharma Pvt. Ltd.
1Y
Phone:+91-7926462688
product: 20054-45-9 2-Mercapto-N-methyl-benzamide 98%
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