Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listN-Eicosanoyl Serotonin

N-Eicosanoyl Serotonin

  • Molecular Weight: 0
  • Update Date: 2023-04-23 13:52:06

What is N-Eicosanoyl Serotonin?

Description

N-Eicosanoyl serotonin is a natural product found in coffee which synergizes with caffeine in protecting the brain in models of α-synucleinopathy.1 It inhibits the PP2A methylesterase maintaining PP2A in a highly active state leading to hypophosphorylated α-synuclein. In mouse models it preserved neuronal integrity and function, diminished neuroinflammation and improved behavioral performance. ?It prevents Aβ-induced impairments in mouse models of Alzheimer’s disease.2,3

The Uses of N-Eicosanoyl Serotonin

N-Eicosanoyl Serotonin is a natural product found in coffee which synergizes with caffeine in protecting the brain in models of α-synucleinopathy. It prevents Aβ-induced impairments in mouse models of Alzheimer’s disease

References

1) Yan?et al.?(2018),?Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson’s disease and DLB; Proc. Natl. Acad. Sci. USA,?115?E12053 2) Asam?et al. (2017),?Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer’s disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid; PLoS One,?12?e0189413 3) Basurto-Islas?et al.?(2014),?Therapeutic benefits of a component of coffee in a rat model of Alzheimer’s disease; Neurobiol. Aging,?35?2701

Properties of N-Eicosanoyl Serotonin

storage temp.  -20°
solubility  Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 20 mg/ml with warming)
form  solid
color  Beige
Stability: Stable for 2 years from date of purchase supplied. Protect from air. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Safety information for N-Eicosanoyl Serotonin

Computed Descriptors for N-Eicosanoyl Serotonin

Related products of tetrahydrofuran

You may like

  • 7726-95-6 Bromine 99.5% AR (4 x 500ml) 99%
    7726-95-6 Bromine 99.5% AR (4 x 500ml) 99%
    7726-95-6
    View Details
  • Formamide 99%
    Formamide 99%
    75-12-7
    View Details
  • 376608-65-0 2-[[(3Ar,4S,6R,6As)-6-Aminotetrahydro-2,2-Dimethyl-4H-Cy 99%
    376608-65-0 2-[[(3Ar,4S,6R,6As)-6-Aminotetrahydro-2,2-Dimethyl-4H-Cy 99%
    376608-65-0
    View Details
  • 2, 4-Pyrimidinediamine 3-Oxide 99%
    2, 4-Pyrimidinediamine 3-Oxide 99%
    74638-76-9
    View Details
  • 111974-72-2 99%
    111974-72-2 99%
    111974-72-2
    View Details
  • 85-81-4 6-Methoxy-8-Nitroquinoline 99%
    85-81-4 6-Methoxy-8-Nitroquinoline 99%
    85-81-4
    View Details
  • 3-Bromo-4,5-Dihydro-1H-Benzo[B]Azepin-2(3H)-One 99%
    3-Bromo-4,5-Dihydro-1H-Benzo[B]Azepin-2(3H)-One 99%
    86499-96-9
    View Details
  • (−)-Dip-Chloride 85116-37-6 99%
    (−)-Dip-Chloride 85116-37-6 99%
    85116-37-6
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.