N-DESMETHYL ROSIGLITAZONE
- CAS NO.:257892-31-2
- Empirical Formula: C17H17N3O3S
- Molecular Weight: 343.4
- MDL number: MFCD08063704
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:12
What is N-DESMETHYL ROSIGLITAZONE?
Description
N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone (Item Nos. 71740 | 71742 | 11884), a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone.
Chemical properties
White Solid
The Uses of N-DESMETHYL ROSIGLITAZONE
A metabolite of Rosiglitazone
The Uses of N-DESMETHYL ROSIGLITAZONE
A metabolite of Rosiglitazone.
What are the applications of Application
N-Desmethyl Rosiglitazone is a Rosiglitazone metabolite
Definition
ChEBI: N-desmethylrosiglitazone is an aromatic ether.
Properties of N-DESMETHYL ROSIGLITAZONE
Melting point: | 177-179°C |
storage temp. | -20°C Freezer |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
color | Off-White to Pale Beige |
Safety information for N-DESMETHYL ROSIGLITAZONE
Computed Descriptors for N-DESMETHYL ROSIGLITAZONE
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION XANTHAN GUM Racecadotril SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN Folic Acid Impurity G Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
5-HYDROXY ROSIGLITAZONE
5-[[4-[2-[pyridin-2-yl(trideuteriomethyl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5-[4-[N-(2-Pyridylamino)ethoxy]benzylidene]thiazolidine-2,4-dione
Rosiglitazone maleate
5-[[4-[1,1,2,2-tetradeuterio-2-[(5-hydroxypyridin-2-yl)-methylamino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5-Hydroxy rosiglitazone-d4
5-(4-Fluorobenzyl)-2,4-thiazolidinedione
N-DESMETHYL ROSIGLITAZONE
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