N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
Synonym(s):N4-[4-(2-Bromo-4,5-difluorophenoxy)phenyl)]-L-asparagine
- CAS NO.：868359-05-1
- Empirical Formula: C16H13BrF2N2O4
- Molecular Weight: 415.19
- MDL number: MFCD09971111
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
![N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Structural](https://img.chemicalbook.in//CAS/GIF/868359-05-1.gif)
What is N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE?
The Uses of N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
WAY 213613 is a selective non-substrate inhibitor of EAAT2. It is used in the methods of treating or inhibiting onset of Huntington''s disease with gene modulatory compounds.
What are the applications of Application
WAY 213613 is a selective non-substrate inhibitor of EAAT2
Biological Activity
Potent, non-substrate inhibitor of EAAT2 (GLT-1) that displays > 44-fold selectivity over EAAT1 and EAAT3 (IC 50 values are 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1 respectively). Exhibits no activity towards ionotropic and metabotropic glutamate receptors.
storage
Desiccate at RT
Properties of N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
| Boiling point: | 565.6±50.0 °C(Predicted) |
| Density | 1.664±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | DMSO: >10mg/mL |
| form | white powder |
| pka | 2.38±0.10(Predicted) |
| color | White to off-white |
Safety information for N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
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