N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
- CAS NO.：300842-64-2
- Empirical Formula: C21H17BrN4
- Molecular Weight: 405.29
- MDL number: MFCD17014834
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-09 19:38:33
What is N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine?
The Uses of N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
NVP-ACC789, is an inhibitor of human VEGFR-1, VEGFR-2 (mouse VEGFR-2), VEGFR-3 and PDGFR-β with IC50s of 0.38, 0.02 (0.23), 0.18, 1.4 μM, respectively.
Properties of N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
| Boiling point: | 607.7±55.0 °C(Predicted) |
| Density | 1.441 |
| storage temp. | Store at -20°C |
| solubility | DMSO:13.0(Max Conc. mg/mL);32.08(Max Conc. mM) DMF:0.5(Max Conc. mg/mL);1.23(Max Conc. mM) DMF:PBS (pH 7) (1:10):0.09(Max Conc. mg/mL);0.22(Max Conc. mM) Ethanol:0.2(Max Conc. mg/mL);0.49(Max Conc. mM) |
| form | A crystalline solid |
| pka | 5.46±0.10(Predicted) |
| color | Light yellow to yellow |
Safety information for N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
Computed Descriptors for N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
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