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HomeProduct name listN-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine

N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine

N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine Structural

What is N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine?

The Uses of N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine

NVP-ACC789, is an inhibitor of human VEGFR-1, VEGFR-2 (mouse VEGFR-2), VEGFR-3 and PDGFR-β with IC50s of 0.38, 0.02 (0.23), 0.18, 1.4 μM, respectively.

Properties of N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine

Boiling point: 607.7±55.0 °C(Predicted)
Density  1.441
storage temp.  Store at -20°C
solubility  DMSO:13.0(Max Conc. mg/mL);32.08(Max Conc. mM)
DMF:0.5(Max Conc. mg/mL);1.23(Max Conc. mM)
DMF:PBS (pH 7) (1:10):0.09(Max Conc. mg/mL);0.22(Max Conc. mM)
Ethanol:0.2(Max Conc. mg/mL);0.49(Max Conc. mM)
form  A crystalline solid
pka 5.46±0.10(Predicted)
color  Light yellow to yellow

Safety information for N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine

Computed Descriptors for N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine

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