MYCOPHENOLIC ACID GLUCURONIDE
- CAS NO.:31528-44-6
- Empirical Formula: C23H28O12
- Molecular Weight: 496.46
- MDL number: MFCD09878308
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:35
What is MYCOPHENOLIC ACID GLUCURONIDE?
Chemical properties
Off-White Solid
The Uses of MYCOPHENOLIC ACID GLUCURONIDE
A metabolite of Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monoph osphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
The Uses of MYCOPHENOLIC ACID GLUCURONIDE
A metabolite of Mycophenolic Acid (M831500), an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
What are the applications of Application
Mycophenolic acid β-D-glucuronide is an inhibitor of lymphocyte proliferation via selective IMPDH inhibition
General Description
A Certified Spiking Solution? for use in therapeutic drug monitoring analyses of serum or whole blood by HPLC or LCMS. The glucuronide, also known as MPAG, is the primary metabolite of the immunosuppressant mycophenolic acid and is monitored by clinical labs to ensure patients remain within the drug′s therapeutic range.
Properties of MYCOPHENOLIC ACID GLUCURONIDE
Melting point: | 98-100°C |
Boiling point: | 875.7±65.0 °C(Predicted) |
Density | 1.502±0.06 g/cm3(Predicted) |
Flash point: | 2℃ |
storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
form | Solid |
pka | 2.76±0.70(Predicted) |
color | White to Pale Beige |
Stability: | Hygroscopic |
Safety information for MYCOPHENOLIC ACID GLUCURONIDE
Signal word | Danger |
Pictogram(s) |
Flame Flammables GHS02 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H225:Flammable liquids H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P337+P313:IF eye irritation persists: Get medical advice/attention. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for MYCOPHENOLIC ACID GLUCURONIDE
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