mPEG8-Alkyne
- CAS NO.:880081-81-2
- Empirical Formula: C20H38O9
- Molecular Weight: 422.51
- MDL number: MFCD31656935
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:23
What is mPEG8-Alkyne?
Biological Activity
m-PEG8-O-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of mPEG8-Alkyne
Boiling point: | 468.8±40.0 °C(Predicted) |
Density | 1.057±0.06 g/cm3(Predicted) |
form | Liquid |
color | Colorless to light yellow |
Safety information for mPEG8-Alkyne
Computed Descriptors for mPEG8-Alkyne
New Products
Tubulysin M Tubulysin G Tubulysin B Tubulysin H 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE CYCLOBUTYLAMINE HYDROCHLORIDE 2H-Pyran, 4-ethynyltetrahydro- 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 2,2-Difluoropropylamine hydrochloride 2,2-Difluoropropanol 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
mPEG24-Propyne
MPEG3-Propyne
Proparyl-PEG5-methane
MPEG16-Propyne
mPEG12-Propyne
mPEG36-Propyne
mPEG11-Propyne
Triethylene Glycol 2-Bromoethyl Methyl Ether
You may like
-
(R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateView Details
2416850-45-6 -
methyl 3-fluoro-4- thiomorpholino phenylcarbamateView Details
2760359-22-4 -
Fuel shell 98%View Details
-
4,6-dichloro-2-propylthiopyrimidine-5-amine 145783-15-9 98%View Details
145783-15-9 -
Hydrogen Gas 98%View Details
-
151767-02-1 Montelukast Sodium IP/USP 98%View Details
151767-02-1 -
Valacyclovir Hydrochloride IH 98%View Details
124832-27-5 -
2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 98%View Details
142569-70-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.