mPEG8-Alkyne
- CAS NO.：880081-81-2
- Empirical Formula: C20H38O9
- Molecular Weight: 422.51
- MDL number: MFCD31656935
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is mPEG8-Alkyne?
Biological Activity
m-PEG8-O-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of mPEG8-Alkyne
| Boiling point: | 468.8±40.0 °C(Predicted) |
| Density | 1.057±0.06 g/cm3(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for mPEG8-Alkyne
Computed Descriptors for mPEG8-Alkyne
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