MPEG16-Propyne
- CAS NO.:2169967-47-7
- Empirical Formula: C36H70O17
- Molecular Weight: 774.93
- MDL number: MFCD27977517
- Update Date: 2023-09-20 16:43:00
What is MPEG16-Propyne?
Biological Activity
Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Safety information for MPEG16-Propyne
New Products
Tubulysin F 2,2-diethoxyethanethioamide Tubulysin C (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin I Tubulysin M 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 3-Aminocyclobutanone hydrochloride 4,4-DIFLUOROPIPERIDINE 2,2-Difluoropropylamine hydrochloride 3-N-BOC-(S)-AMINO BUTYRONITRILE 4-(Benzyloxy)-3-bromophenylacetic Acid (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Imeglimin Hydrochloride IH 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell Lubiprostone Magnesium Trisilicate Latanoprostene Bunod Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateRelated products of tetrahydrofuran
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