MPEG16-Propyne
- CAS NO.：2169967-47-7
- Empirical Formula: C36H70O17
- Molecular Weight: 774.93
- MDL number: MFCD27977517
- Update Date: 2024-10-28 23:16:16
What is MPEG16-Propyne?
Biological Activity
Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Safety information for MPEG16-Propyne
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