MPEG16-NH2
- CAS NO.：907577-50-8
- Empirical Formula: C33H69NO16
- Molecular Weight: 735.9
- MDL number: MFCD31656924
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-28 13:39:29
What is MPEG16-NH2?
Biological Activity
m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of MPEG16-NH2
| Boiling point: | 699.1±50.0 °C(Predicted) |
| Density | 1.084±0.06 g/cm3(Predicted) |
| pka | 8.74±0.10(Predicted) |
Safety information for MPEG16-NH2
Computed Descriptors for MPEG16-NH2
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