MPEG16-NH2
- CAS NO.:907577-50-8
- Empirical Formula: C33H69NO16
- Molecular Weight: 735.9
- MDL number: MFCD31656924
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-28 13:39:29
What is MPEG16-NH2?
Biological Activity
m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of MPEG16-NH2
Boiling point: | 699.1±50.0 °C(Predicted) |
Density | 1.084±0.06 g/cm3(Predicted) |
pka | 8.74±0.10(Predicted) |
Safety information for MPEG16-NH2
Computed Descriptors for MPEG16-NH2
New Products
(R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin C Tubulysin E 2,2-diethoxyethanethioamide Potassium HMDS (1.0 M in THF) CYCLOBUTYLAMINE HYDROCHLORIDE 4,4-DIFLUOROCYCLOHEXANAMINE 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 4-(Benzyloxy)-3-bromophenylacetic Acid tetrahydro-4-methyl-2H-pyran Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell Calcium Sodium Phosphosilicate IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
MPEG6-CH2CH2COOH
Amino-PEG2-acid
alpha-aMine-oMega-propionic acid hexaethylene glycol
HS-PEG8-CH2CH2COOH
2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane-28-thiol
DODECAETHYLENE GLYCOL
MPEG3-NHS
PENTAETHYLENE GLYCOL MONOMETHYL ETHER
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