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HomeProduct name listMPEG16-NH2

MPEG16-NH2

MPEG16-NH2 Structural

What is MPEG16-NH2?

Biological Activity

m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Properties of MPEG16-NH2

Boiling point: 699.1±50.0 °C(Predicted)
Density  1.084±0.06 g/cm3(Predicted)
pka 8.74±0.10(Predicted)

Safety information for MPEG16-NH2

Computed Descriptors for MPEG16-NH2

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