Midecamycin Acetate
- CAS NO.:55881-07-7
- Empirical Formula: C45H71NO17
- Molecular Weight: 898.046
- MDL number: MFCD00869591
- EINECS: 2598796
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-21 16:56:50
What is Midecamycin Acetate?
Description
Miokamycin (midecamycin acetate) is a macrolide antibiotic useful in the treatment of respiratory tract, dermatological and surgical infections due to grampositive bacteria and mycoplasmas.
Originator
Meiji Seika (Japan)
brand name
MIOCAMYCIN
Pharmaceutical Applications
A semisynthetic diacetyl derivative of midecamycin A1. It is generally less active than erythromycin and some strains of H. influenzae and E. faecalis are resistant. It is rapidly and extensively metabolized, though some metabolites retain antibacterial activity.
Absorption of the dry formulation is unaffected by food, whereas that of the oral suspension is delayed. In various studies the peak plasma concentration was 1.65, 1.31–3 and 1.3–2.7 mg/L after doses of 400, 600 and 800 mg, respectively.
It is said to exhibit less toxicity than earlier macrolides. Attention has been paid to its interaction with theophylline, which resembles that of other macrolides. It is of limited availability.
Properties of Midecamycin Acetate
Melting point: | ~220° (with coloration) |
Boiling point: | 878.7±65.0 °C(Predicted) |
alpha | D25 -53° (c = 1.0 in chloroform); D20 -74° (c = 1 in methanol) |
Density | 1.20±0.1 g/cm3(Predicted) |
pka | 13.06±0.70(Predicted) |
Safety information for Midecamycin Acetate
Computed Descriptors for Midecamycin Acetate
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
You may like
-
Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid SaltView Details
-
Dechloro DesloratadineView Details
-
Dehydro DesloratadineView Details
-
Edoxaban Impurity 57View Details
2089454-69-1 -
Eltrombopag N-Oxide ImpurityView Details
2734533-17-4 -
Empagliflozin Bromo ImpurityView Details
-
Glycopyrronium Bromide EP Impurity IView Details
1404617-94-2 -
Ipratropium EP Impurity BView Details
58073-59-9