METHYLMALONYL COENZYME A LITHIUM

Synonym(s):α-Methylmalonyl coenzyme A tetralithium salt;MM-CoA

CAS NO.：104809-02-1
Empirical Formula: C25H41LiN7O19P3S
Molecular Weight: 875.55
MDL number: MFCD10567443
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

METHYLMALONYL COENZYME A LITHIUM Structural

What is METHYLMALONYL COENZYME A LITHIUM?

The Uses of METHYLMALONYL COENZYME A LITHIUM

Methylmalonyl coenzyme A (CoA) has been used in the preparation of the calibration curve in ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS). It has also been used in the measurement of methylmalonyl-CoA mutase and methylmalonyl-CoA epimerase activity.

Biochem/physiol Actions

Methylmalonyl coenzyme A (CoA) is a catabolite of odd-chain fatty acids, cholesterol and few amino acids like valine, isoleucine, methionine, threonine. It is produced by the activity of the enzyme propionyl-CoA carboxylase(PCC). Methylmalonyl coenzyme A (CoA) is converted to succinyl-CoA by the methylmalonyl-CoA mutase (MCM) and vitamin B12 as the cofactor. Either a low MCM activity or an altered metabolism of vitamin B12 causes the inherited metabolic disease methylmalonic acidemia (MMA).

Properties of METHYLMALONYL COENZYME A LITHIUM

storage temp.	-20°C
solubility	H₂O: 50 mg/mL, clear, colorless
form	Solid
color	Off-white to light yellow

Safety information for METHYLMALONYL COENZYME A LITHIUM

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.