METHYLMALONYL COENZYME A LITHIUM
Synonym(s):α-Methylmalonyl coenzyme A tetralithium salt;MM-CoA
- CAS NO.：104809-02-1
- Empirical Formula: C25H41LiN7O19P3S
- Molecular Weight: 875.55
- MDL number: MFCD10567443
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:11
What is METHYLMALONYL COENZYME A LITHIUM?
The Uses of METHYLMALONYL COENZYME A LITHIUM
Methylmalonyl coenzyme A (CoA) has been used in the preparation of the calibration curve in ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS). It has also been used in the measurement of methylmalonyl-CoA mutase and methylmalonyl-CoA epimerase activity.
Biochem/physiol Actions
Methylmalonyl coenzyme A (CoA) is a catabolite of odd-chain fatty acids, cholesterol and few amino acids like valine, isoleucine, methionine, threonine. It is produced by the activity of the enzyme propionyl-CoA carboxylase(PCC). Methylmalonyl coenzyme A (CoA) is converted to succinyl-CoA by the methylmalonyl-CoA mutase (MCM) and vitamin B12 as the cofactor. Either a low MCM activity or an altered metabolism of vitamin B12 causes the inherited metabolic disease methylmalonic acidemia (MMA).
Properties of METHYLMALONYL COENZYME A LITHIUM
| storage temp. | -20°C |
| solubility | H2O: 50 mg/mL, clear, colorless |
| form | Solid |
| color | Off-white to light yellow |
Safety information for METHYLMALONYL COENZYME A LITHIUM
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for METHYLMALONYL COENZYME A LITHIUM
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