Methyl picolinate

CAS NO.：2459-07-6
Empirical Formula: C7H7NO2
Molecular Weight: 137.14
MDL number: MFCD00038038
EINECS: 219-545-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-01 18:09:03

What is Methyl picolinate?

Chemical properties

Colorless to yellow liquid

The Uses of Methyl picolinate

Methyl picolinate is used as pharmaceutical intermediate.

Definition

ChEBI: Methyl picolinate is a member of pyridines and an aromatic carboxylic acid.

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 5614, 1951 DOI: 10.1021/ja01156a035

General Description

Methyl picolinate (MP) exists in two conformers i.e s-trans and s-cis. Molecular structure of these forms has been investigated by gas electron diffraction.

Properties of Methyl picolinate

Melting point:	19℃
Boiling point:	95 °C1 mm Hg(lit.)
Density	1.137 g/mL at 25 °C(lit.)
refractive index	n20/D 1.521(lit.)
Flash point:	217 °F
storage temp.	Inert atmosphere,Room Temperature
form	Crystalline Powder
pka	pK1:2.21(＋1) (25°C)
color	White
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	2459-07-6(CAS DataBase Reference)
NIST Chemistry Reference	2-Pyridinecarboxylic acid, methyl ester(2459-07-6)
EPA Substance Registry System	2-Pyridinecarboxylic acid, methyl ester (2459-07-6)

Safety information for Methyl picolinate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.