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HomeProduct name listMETHYL 4-CHLOROBENZOATE

METHYL 4-CHLOROBENZOATE

  • CAS NO.:1126-46-1
  • Empirical Formula: C8H7ClO2
  • Molecular Weight: 170.59
  • MDL number: MFCD00000621
  • EINECS: 214-420-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:32
METHYL 4-CHLOROBENZOATE Structural

What is METHYL 4-CHLOROBENZOATE?

Chemical properties

COLOURLESS TO WHITE CRYSTALS

The Uses of METHYL 4-CHLOROBENZOATE

Methyl 4-chlorobenzoate was used in quantitative determination of chlorophenoxyisobutyrate (CPIB) and salicylic acid, the metabolites of clofibrate and aspirin, by GC-MS method.

Synthesis Reference(s)

Synthesis, p. 790, 1981 DOI: 10.1055/s-1981-29595

General Description

Methyl 4-chlorobenzoate undergoes room temperature Pd-mediated hydrodehalogenation with KF and polymethylhydrosiloxane (PMHS) to yield methyl benzoate. It undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid in the presence of bis-carbene palladium complex catalyst to yield methyl-(4-phenyl)-benzoate.

Properties of METHYL 4-CHLOROBENZOATE

Melting point: 42-44 °C (lit.)
Boiling point: 136-137°C 10mm
Density  1,382 g/cm3
refractive index  1.5800 (estimate)
Flash point: 224 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
color  Off-White Low Melting
Merck  14,2125
BRN  1564310
CAS DataBase Reference 1126-46-1(CAS DataBase Reference)
EPA Substance Registry System Benzoic acid, 4-chloro-, methyl ester (1126-46-1)

Safety information for METHYL 4-CHLOROBENZOATE

Computed Descriptors for METHYL 4-CHLOROBENZOATE

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