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HomeProduct name listMETHIOTHEPIN MALEATE

METHIOTHEPIN MALEATE

METHIOTHEPIN MALEATE Structural

What is METHIOTHEPIN MALEATE?

The Uses of METHIOTHEPIN MALEATE

Methiothepin Maleate exhibits anticonvulsant property and it is able to suppress pentylenetetrazol induced fos expression in zebrafish. In addition, Methiothepin Maleate is a 5-HT antagonist.

The Uses of METHIOTHEPIN MALEATE

Biochemical tool in serotonin receptor binding studies.

What are the applications of Application

Methiothepin maleate is a potent 5-HT2 and active 5-HT1 antagonist

Definition

ChEBI: A maleate salt obtained by reaction of methiothepin with one equivalent of maleic acid. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays ffinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).

Properties of METHIOTHEPIN MALEATE

Melting point: 171-173°
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Soluble to 100 mM in DMSO
form  Powder

Safety information for METHIOTHEPIN MALEATE

Computed Descriptors for METHIOTHEPIN MALEATE

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