MECLOCYCLINE SULFOSALICYLATE SALT
Synonym(s):Meclocycline sulfosalicylate salt
- CAS NO.:73816-42-9
- Empirical Formula: C29H27ClN2O14S
- Molecular Weight: 695.05
- MDL number: MFCD00865070
- EINECS: 277-614-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-08 20:21:46
What is MECLOCYCLINE SULFOSALICYLATE SALT?
The Uses of MECLOCYCLINE SULFOSALICYLATE SALT
Meclocycline Sulfosalicylate Salt is a salt prepared from demeclocycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in solution with 2-hydroxy-3-carboxybenenesulphonic acid. Like all tetracyclines, meclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. The unusual complex counter-ion is likely to add an antiseptic component to the use of the compound for skin infections.
The Uses of MECLOCYCLINE SULFOSALICYLATE SALT
Antibacterial;Antibacterial
The Uses of MECLOCYCLINE SULFOSALICYLATE SALT
Meclocycline is a tetracycline antibiotic that is topically used for skin infections and irritations.
brand name
Meclan (Johnson & Johnson).
General Description
Meclocycline, 7-chloro-6-deoxy-6-demethyl-6-methylene-5-oxytetracycline sulfosalicylate (Meclan), is a semisyntheticderivative prepared from oxytetracycline.Although meclocycline has been used in Europe for manyyears, it became available only relatively recently in theUnited States for a single therapeutic indication, the treatmentof acne. It is available as the sulfosalicylate salt in a1% cream.
Meclocycline sulfosalicylate is a bright yellow, crystallinepowder that is slightly soluble in water and insolublein organic solvents. It is light sensitive and should be storedin light-resistant containers.
Properties of MECLOCYCLINE SULFOSALICYLATE SALT
Melting point: | >193°C (dec.) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | methanol: soluble10ML, clear, very dark yellow (200 mg + 10 mL MeOH) |
form | Solid |
color | yellow-green powder |
Stability: | Hygroscopic |
Safety information for MECLOCYCLINE SULFOSALICYLATE SALT
Computed Descriptors for MECLOCYCLINE SULFOSALICYLATE SALT
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