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HomeProduct name listMECLOCYCLINE SULFOSALICYLATE SALT

MECLOCYCLINE SULFOSALICYLATE SALT

Synonym(s):Meclocycline sulfosalicylate salt

  • CAS NO.:73816-42-9
  • Empirical Formula: C29H27ClN2O14S
  • Molecular Weight: 695.05
  • MDL number: MFCD00865070
  • EINECS: 277-614-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-08 20:21:46
MECLOCYCLINE SULFOSALICYLATE SALT Structural

What is MECLOCYCLINE SULFOSALICYLATE SALT?

The Uses of MECLOCYCLINE SULFOSALICYLATE SALT

Meclocycline Sulfosalicylate Salt is a salt prepared from demeclocycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in solution with 2-hydroxy-3-carboxybenenesulphonic acid. Like all tetracyclines, meclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. The unusual complex counter-ion is likely to add an antiseptic component to the use of the compound for skin infections.

The Uses of MECLOCYCLINE SULFOSALICYLATE SALT

Antibacterial;Antibacterial

The Uses of MECLOCYCLINE SULFOSALICYLATE SALT

Meclocycline is a tetracycline antibiotic that is topically used for skin infections and irritations.

brand name

Meclan (Johnson & Johnson).

General Description

Meclocycline, 7-chloro-6-deoxy-6-demethyl-6-methylene-5-oxytetracycline sulfosalicylate (Meclan), is a semisyntheticderivative prepared from oxytetracycline.Although meclocycline has been used in Europe for manyyears, it became available only relatively recently in theUnited States for a single therapeutic indication, the treatmentof acne. It is available as the sulfosalicylate salt in a1% cream.
Meclocycline sulfosalicylate is a bright yellow, crystallinepowder that is slightly soluble in water and insolublein organic solvents. It is light sensitive and should be storedin light-resistant containers.

Properties of MECLOCYCLINE SULFOSALICYLATE SALT

Melting point: >193°C (dec.)
storage temp.  Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility  methanol: soluble10ML, clear, very dark yellow (200 mg + 10 mL MeOH)
form  Solid
color  yellow-green powder
Stability: Hygroscopic

Safety information for MECLOCYCLINE SULFOSALICYLATE SALT

Computed Descriptors for MECLOCYCLINE SULFOSALICYLATE SALT

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