Mal-PEG8-COOH
- CAS NO.：1334177-86-4
- Empirical Formula: C26H44N2O13
- Molecular Weight: 592.63
- MDL number: MFCD13184956
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:06
What is Mal-PEG8-COOH?
Description
Mal-amido-PEG8-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
The Uses of Mal-PEG8-COOH
31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic Acid is reactant in the light-induced endosomal lysis events in fibroblast, normal, and carcinoma cell lines using a colloidal mesoporous silica (CMS) nanoparticle.
Properties of Mal-PEG8-COOH
| Boiling point: | 747.9±60.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| pka | 4.28±0.10(Predicted) |
| form | Solid-Liquid Mixture |
| color | Colorless to off-white |
Safety information for Mal-PEG8-COOH
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Mal-PEG8-COOH
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