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HomeProduct name listMal-PEG8-COOH

Mal-PEG8-COOH

Mal-PEG8-COOH Structural

What is Mal-PEG8-COOH?

Description

Mal-amido-PEG8-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

The Uses of Mal-PEG8-COOH

31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic Acid is reactant in the light-induced endosomal lysis events in fibroblast, normal, and carcinoma cell lines using a colloidal mesoporous silica (CMS) nanoparticle.

Properties of Mal-PEG8-COOH

Boiling point: 747.9±60.0 °C(Predicted)
Density  1?+-.0.06 g/cm3(Predicted)
pka 4.28±0.10(Predicted)
form  Solid-Liquid Mixture
color  Colorless to off-white

Safety information for Mal-PEG8-COOH

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Mal-PEG8-COOH

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