Mal-PEG2-Val-Cit-amido-PAB-OH
- CAS NO.：2055041-38-6
- Empirical Formula: C29H42N6O9
- Molecular Weight: 618.68
- MDL number: MFCD29918233
- Update Date: 2024-03-29 18:52:01
What is Mal-PEG2-Val-Cit-amido-PAB-OH?
Description
Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The maleimide group is reactive toward thiol groups between pH 6.5 to 7.5. PEG chain increases the water solubility of the compound.
Properties of Mal-PEG2-Val-Cit-amido-PAB-OH
| Boiling point: | 948.4±65.0 °C(Predicted) |
| Density | 1.294±0.06 g/cm3(Predicted) |
| solubility | Soluble in DMSO, DMF |
| pka | 13.41±0.70(Predicted) |
Safety information for Mal-PEG2-Val-Cit-amido-PAB-OH
Computed Descriptors for Mal-PEG2-Val-Cit-amido-PAB-OH
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium 3-Bromopyrazole (3aR,4R,5R,6aS)-hexahydro-5-Triethyl silyloxy-4-((E)-3-oxo-5-phenylpent-1- enyl)cyclopenta[b]furan-2-one. 1-Chlorocarbonyl-4-piperidinopiperidine 1-Bromo-4-phenyl-2-Butanone 4-Amino-2-fluoro-N-methylbenzamide 1,1'-Carbonyldiimidazole SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTIONRelated products of tetrahydrofuran
You may like
-
![Dimethyl [2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]phosphonate 99%](https://img.chemicalbook.in//Content/image/CP5.jpg)
Dimethyl [2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]phosphonate 99%View Details
54094-19-8 -
85-81-4 99%View Details
85-81-4 -
Cyclopentane carboxxylic acid 3400-45-1 99%View Details
3400-45-1 -
208111-98-2 (3aR,4R,5R,6aS)-5-(Benzoyloxy)hexahydro-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten- 1-yl]-2H-cyclopenta[b]furan-2-one 99%View Details
208111-98-2 -
2033-24-1 99%View Details
2033-24-1 -
Meldrums acid 2033-24-1 99%View Details
2033-24-1 -
Cyaclopentane carboxylic acid 99%View Details
3400-45-1 -
2-Aminopyridine 504-29-0 99%View Details
504-29-0
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.