Mal-amido-PEG7-acid
- CAS NO.：2112731-42-5
- Empirical Formula: C24H40N2O12
- Molecular Weight: 548.58
- MDL number: MFCD30723255
- Update Date: 2024-11-19 23:02:33
What is Mal-amido-PEG7-acid?
The Uses of Mal-amido-PEG7-acid
Mal-amido-peg7-acid is a useful research chemical, a PEG linker and a PEG reagent.
Biological Activity
Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Safety information for Mal-amido-PEG7-acid
New Products
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