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HomeProduct name listMafenide hydrochloride

Mafenide hydrochloride

Synonym(s):4-Homosulfanilamide;Mafenide;Marfanil

  • CAS NO.:138-37-4
  • Empirical Formula: C7H11ClN2O2S
  • Molecular Weight: 222.69
  • MDL number: MFCD00013005
  • EINECS: 205-325-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-17 08:48:38
Mafenide hydrochloride Structural

What is Mafenide hydrochloride?

The Uses of Mafenide hydrochloride

Antibacterial;Inhibitor of folic acid biosynthesis

Purification Methods

Crystallise the salt from dilute HCl or 95% EtOH and dry it in a vacuum at 100o. It is an antibacterial. [Miller et al. J Am Chem Soc 62 2099 1940, Bergeim & Barker J Am Chem Soc 66 1459 1944.] The sulfate salt has m 254-255o (from aqueous EtOH). [Beilstein 14 III 2223, 14 IV 2799.]

Properties of Mafenide hydrochloride

Melting point: 261-263 °C(lit.)
storage temp.  Inert atmosphere,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
form  neat
form  Solid
color  White
Merck  13,5671
CAS DataBase Reference 138-37-4(CAS DataBase Reference)

Safety information for Mafenide hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H317:Sensitisation, Skin
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for Mafenide hydrochloride

InChIKey SIACJRVYIPXFKS-UHFFFAOYSA-N

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