Lypressin

Synonym(s):[Lys⁸]-Vasopressin;Lysine vasopressin;Lyspressin

CAS NO.：50-57-7
Empirical Formula: C46H65N13O12S2
Molecular Weight: 1056.22
MDL number: MFCD00076754
EINECS: 200-050-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is Lypressin?

The Uses of Lypressin

Lypressin is a neurohypophysial hormone that regulates water, glucose, and salts in blood.

The Uses of Lypressin

Hormone (antidiuretic).

What are the applications of Application

Lypressin is a neurohypophysial hormone that regulates water, glucose, and salts in blood

Definition

ChEBI: (2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloeicos-4-yl]-oxomethyl]-2-pyrrolidinecarboxamide is a cyclic peptide.

brand name

Pitressin (Parke-Davis).

General Description

Lypressin is synthetic 8-L-lysine vasopressin,a polypeptide similar to ADH. The lysine analog isconsidered more stable, and it is absorbed rapidly from thenasal mucosa. Lypressin (Diapid) is pharmaceutically availableas a topical solution, spray, 50 pressor units(185 g)/mL in 5-mL containers. Usual dosage, topical (intranasal),one or more sprays applied to one or both nostrilsone or more times daily.

Metabolism

Not Available

Properties of Lypressin

Boiling point:	1610.4±65.0 °C(Predicted)
Density	1.1080 (rough estimate)
refractive index	1.6700 (estimate)
storage temp.	-20°C
form	Solid
pka	9.90±0.15(Predicted)
color	White to off-white

Safety information for Lypressin

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H332:Acute toxicity,inhalation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P403:Store in a well-ventilated place.

Computed Descriptors for Lypressin

InChIKey	NKWAIKZITYLOMT-DHSVNZEYSA-N
SMILES	C1(N)CSSCC(C(=O)N2C(C(=O)CC(CCCCN)C(=O)NCC(=O)N)CCC2)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC2C=CC(O)=CC=2)NC1=O)CCC(=O)N