LUMIFLAVINE
- CAS NO.:1088-56-8
- Empirical Formula: C13H12N4O2
- Molecular Weight: 256.26
- MDL number: MFCD00042742
- EINECS: 214-125-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 11:41:24
What is LUMIFLAVINE?
Chemical properties
deep yellow powder
The Uses of LUMIFLAVINE
Lumiflavin is a toxic photolysis product of vitamin B2 (R415000).
What are the applications of Application
Lumiflavine is a riboflavin uptake inhibitor used to study riboflavin uptake in intestinal epithelial (Caco-2) and other epithelial cells
Definition
ChEBI: Lumiflavin is a compound showing yellow-green fluorescence, formed by a photolysis of riboflavin in alkaline solution.
Purification Methods
Lumiflavin forms orange crystals upon recrystallisation from 12% aqueous AcOH, or from formic acid. It sublimes at high vacuum. It is freely soluble in CHCl3, but not very soluble in H2O and most organic solvents. In H2O and CHCl3 solution it has a green fluorescence. UV has max at 269, 355 and 445nm ( 38,800, 11,700 and 11,800, respectively) in 0.1N NaOH and 264, 373 and 440nm ( 34,700, 11,400 and 10,400, respectively) in 0.1N HCl, while the UV in CHCl3 has max at 270, 312, 341, 360, 420, 445 and 470nm. [Hemmerich et al. Helv Chim Acta 39 1242 1956, Holiday & Stern Chem Ber 67 1352 1834, Yoneda et al. Chem Pharm Bull Jpn 20 1832 1972, Birch & Moye J Chem Soc 2622 1958, Fluorescence: Kuhn & Moruzzi Chem Ber 67 888 1934, Beilstein 26 III/IV 2539.]
Properties of LUMIFLAVINE
Melting point: | 320°; mp 330° |
storage temp. | 2-8°C |
solubility | Methanol (Very Slightly, Heated, Sonicated), Trifluoroacetic Acid (Very Slightly |
form | powder |
Density | 1.48 g/cm3 |
pka | 10.05±0.70(Predicted) |
color | Dark Yellow to Dark Green |
Merck | 13,5621 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Safety information for LUMIFLAVINE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for LUMIFLAVINE
New Products
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