LEUPEPTIN HEMISULFATE MONOHYDRATE
- CAS NO.：55123-66-5
- Empirical Formula: C20H38N6O4
- Molecular Weight: 426.55
- MDL number: MFCD00198027
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:39
What is LEUPEPTIN HEMISULFATE MONOHYDRATE?
Definition
ChEBI: Leupeptin is a tripeptide composed of N-acetylleucyl, leucyl and argininal residues joined in sequenceby peptide linkages. It is an inhibitor of the calpains, a family of calcium-activated proteases which promote cell death. It has a role as a serine protease inhibitor, a bacterial metabolite, a cathepsin B inhibitor, a calpain inhibitor and an EC 3.4.21.4 (trypsin) inhibitor. It is a tripeptide and an aldehyde. It is a conjugate base of a leupeptin(1+).
Safety Profile
Questionable carcinogen withexperimental neoplastigenic data. When heated todecomposition it emits toxic fumes of NOx.
Properties of LEUPEPTIN HEMISULFATE MONOHYDRATE
| Boiling point: | 541.98°C (rough estimate) |
| Density | 1.1865 (rough estimate) |
| RTECS | YV4205100 |
| refractive index | 1.6000 (estimate) |
| pka | 13.44±0.46(Predicted) |
| form | Powder |
Safety information for LEUPEPTIN HEMISULFATE MONOHYDRATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P405:Store locked up. |
Computed Descriptors for LEUPEPTIN HEMISULFATE MONOHYDRATE
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