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HomeProduct name listLCL-161

LCL-161

LCL-161 Structural

What is LCL-161?

Description

LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitor of apoptosis (IAP) family proteins.

The Uses of LCL-161

LCL 161 is a second mitochondria-derived activator of caspases (SMAC) inhibitor used to prolong patient survival by increasing apoptosis of anti-tumor drugs.

Properties of LCL-161

Boiling point: 713.7±60.0 °C(Predicted)
Density  1.245±0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  ≥25.05 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form  solid
pka 14.25±0.46(Predicted)
color  White to yellow

Safety information for LCL-161

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for LCL-161

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