LAVENDUSTIN C

Description

Lavendustin C, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC₅₀ value of 0.012 μM. Lavendustin C also inhibits pp60^c-src(+) kinase and Ca²⁺ calmodulin-dependent kinase II with IC₅₀ values of 0.5 and 0.2 μM, respectively. At a concentration of 10-150 μM, lavendustin C inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.

Chemical properties

Brown Solid

The Uses of LAVENDUSTIN C

Shows potent tyrosine kinase inhibitory activity

The Uses of LAVENDUSTIN C

Shows potent tyrosine kinase inhibitory activity.

What are the applications of Application

Lavendustin C is an inhibitor of CaMKII

Definition

ChEBI: 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid is an aromatic amine.