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HomeProduct name listLAURDAN

LAURDAN

Synonym(s):2-(Dimethylamino)-6-dodecanoylnaphthalene;Laurdan;N,N-Dimethyl-6-dodecanoyl-2-naphthylamine

LAURDAN Structural

What is LAURDAN?

The Uses of LAURDAN

N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasmamembranes.

The Uses of LAURDAN

6-Dodecanoyl-N,N-dimethyl-2-naphthylamine is a fluorescent membrane probe used in phospholipid multilamellar aggregates which distinguishes between phase transitions, phase fluctuations and the coexistence of phase domains. Studies indicate that the bulky and highly hydrated polar head groups of glycosphingolipids interact well with 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine. The fluorescence is derived from the naphthalene moiety, in which a small dipole moment exists due to a partial charge separation between the 2-dimethylamino and the 6-carbonyl residues. This fluorescent tag is ideal to study dipolar relaxation because this compound emits different light depending on the environment it is in. For instance, 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine emits red light in a polar solvent and

storage

Store at -20°C

Properties of LAURDAN

Melting point: 88 °C(lit.)
Boiling point: 497.4±20.0 °C(Predicted)
Density  0.987±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMF: soluble
form  Solid
pka 4.44±0.40(Predicted)
color  Off-White to Pale Brown
BRN  7379104

Safety information for LAURDAN

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for LAURDAN

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