LAURDAN
Synonym(s):2-(Dimethylamino)-6-dodecanoylnaphthalene;Laurdan;N,N-Dimethyl-6-dodecanoyl-2-naphthylamine
- CAS NO.:74515-25-6
- Empirical Formula: C24H35NO
- Molecular Weight: 353.54
- MDL number: MFCD00467560
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-06 19:41:26
What is LAURDAN?
The Uses of LAURDAN
N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasmamembranes.
The Uses of LAURDAN
6-Dodecanoyl-N,N-dimethyl-2-naphthylamine is a fluorescent membrane probe used in phospholipid multilamellar aggregates which distinguishes between phase transitions, phase fluctuations and the coexistence of phase domains. Studies indicate that the bulky and highly hydrated polar head groups of glycosphingolipids interact well with 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine. The fluorescence is derived from the naphthalene moiety, in which a small dipole moment exists due to a partial charge separation between the 2-dimethylamino and the 6-carbonyl residues. This fluorescent tag is ideal to study dipolar relaxation because this compound emits different light depending on the environment it is in. For instance, 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine emits red light in a polar solvent and
storage
Store at -20°C
Properties of LAURDAN
Melting point: | 88 °C(lit.) |
Boiling point: | 497.4±20.0 °C(Predicted) |
Density | 0.987±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMF: soluble |
form | Solid |
pka | 4.44±0.40(Predicted) |
color | Off-White to Pale Brown |
BRN | 7379104 |
Safety information for LAURDAN
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for LAURDAN
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