(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
- CAS NO.:188416-35-5
- Empirical Formula: C16H13ClF3N5O
- Molecular Weight: 383.76
- MDL number: MFCD08063925
- EINECS: 606-140-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:55
What is (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride?
Chemical properties
Off-White Solid
The Uses of (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
An achiral intermediate of Voriconazole (V760000).
What are the applications of Application
rac-6-Chloro Voriconazole is an achiral intermediate of Voriconazole
Properties of (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
Melting point: | 183-187°C |
Boiling point: | 529.9±60.0 °C(Predicted) |
Density | 1.51 |
storage temp. | Refrigerator |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 11.44±0.29(Predicted) |
form | Solid |
color | Off-White |
CAS DataBase Reference | 188416-35-5(CAS DataBase Reference) |
Safety information for (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
Computed Descriptors for (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
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product: 188416-35-5 (2R,3S)/(2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride (or) Chloro Voriconazole 98%
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6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine
Voriconazole Impurity 53
1,2,4-Triazole
2-Chloro-2',4'-difluoroacetophenone
Pyrimidine, 4-bromo-6-(1-bromoethyl)-5-fluoro-
Pyrimidine, 4,4'-(1,2-dimethyl-1,2-ethanediyl)bis[2,6-dichloro-5-fluoro- (9CI)
(2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
1-Butanesulfonic acid, 4-hydroxy-, methyl ester
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